S. Ishikawa et al., IS IT NECESSARY TO DECORTICATE SEGMENTALLY INSTRUMENTED SPINES TO ACHIEVE FUSION, Spine (Philadelphia, Pa. 1976), 19(15), 1994, pp. 1686-1690
Study Design. The effects of spinal instrumentation and decortication
on spinal arthrodesis rates-when performed independently and when used
together-were studied in an experimental animal model. Materials and
Methods. Fifty-two immature New Zealand white rabbits underwent six di
fferent spinal procedures. The animals were killed six weeks postopera
tively and their spines were evaluated by gross examination, radiograp
hy, manual stress testing, and histologic means. Results. The addition
of rigid instrumentation to autologous iliac grafting significantly i
mproved fusion rates in animals that were not decorticated. However, w
hen decortication was done, a statistically significant improvement co
uld not be documented. The addition of decortication to autologous ili
ac grafting significantly improved fusion rates in noninstrumented spi
nes, but in instrumented spines, a statistically significant improveme
nt could not be demonstrated.