Js. Ko et al., REGULATION OF PHOSPHATIDYLINOSITOL-CERAMIDE PHOSPHOINOSITOL TRANSFERASE IN SACCHAROMYCES-CEREVISIAE, Journal of bacteriology, 176(16), 1994, pp. 5181-5183
Maximal phosphatidylinositol:ceramide phosphoinositol transferase acti
vity was measured in yeast cells harvested during the exponential phas
e of growth. The addition of inositol to the growth medium resulted in
a twofold increase in IPC synthase activity in cells grown in the pre
sence or absence of exogenous choline. Enzyme activity was not regulat
ed in yeast inositol biosynthesis regulatory mutants by the addition o
f inositol to the growth medium.