THE ROLE OF PARATHYROID HORMONE-RELATED PROTEIN IN CALCIUM HOMEOSTASIS IN THE FETAL PIG

Authors
ABBAS SK RATCLIFFE WA MONIZ C DIXIT M CAPLE IW SILVER M FOWDEN A CARE AD
Citation
Sk. Abbas et al., THE ROLE OF PARATHYROID HORMONE-RELATED PROTEIN IN CALCIUM HOMEOSTASIS IN THE FETAL PIG, Experimental physiology, 79(4), 1994, pp. 527-536
Citations number
17
Categorie Soggetti
Physiology
Journal title
Experimental physiology → ACNP
ISSN journal
09580670
Volume
79
Issue
4
Year of publication
1994
Pages
527 - 536
Database
ISI
SICI code
0958-0670(1994)79:4<527:TROPHP>2.0.ZU;2-O
Abstract
The concentrations of plasma parathyroid hormone-like bioactivity and parathyroid hormone-related protein (1-86) (PTHrP) immunoreactivity we re both higher in fetal pigs than in their mothers during the last 3 w eeks of gestation. Both activities changed inversely with alterations in the plasma ionized calcium concentration. The data suggest that PTH rP may have a role in calcium homeostasis in the fetal pig, similar to its postulated role in sheep in the stimulation of calcium transport across the placenta.