UV-A-PROVOKED LOCALIZED BULLOUS PEMPHIGOID

Citation
A. Pfau et al., UV-A-PROVOKED LOCALIZED BULLOUS PEMPHIGOID, Acta dermato-venereologica, 74(4), 1994, pp. 314-316
Citations number
25
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
ISSN journal
00015555
Volume
74
Issue
4
Year of publication
1994
Pages
314 - 316
Database
ISI
SICI code
0001-5555(1994)74:4<314:ULBP>2.0.ZU;2-E
Abstract
A 71-year-old woman had noticed the development of blisters on her for ehead 4 months before she was referred to our department. Treatment wi th oral corticosteroids resulted in complete healing, but new blisters subsequently developed on the face, neck and backs of the hands. Afte r the possibility of phototoxic and photoallergic reactions, as well a s an abnormal porphyrin profile, had been excluded, the diagnosis of b ullous pemphigoid was made by histological and direct immunofluorescen t examination. UV-A provocation on the upper arm produced lesions hist ologically and immunohistochemically typical of bullous pemphigoid. Of particular importance was the fact that the blisters were limited str ictly to light-exposed skin areas.