A seven-year-old female German shepherd dog was presented with a histo
ry of anorexia, weight loss and fever of three months' duration. On ge
neral examination she showed a marked behavioural change represented b
y episodic excitement and 'fly snapping'. A general blood screening sh
owed neutrophilia with left shift and hyperalbuminaemia. Survey radiog
raphs were taken and a mass was identified in the cranial mediastinum.
Cytological examination of fine needle aspiration smears of the mass
yielded a presumptive diagnosis of lymphoma. The dog was euthanased an
d necropsy findings concluded that the primary tumour was a thymoma; m
etastases were found in the choroid plexus, leptomeninges, cerebral co
rtex and hippocampus.