Six patients with upper urinary tract tumors were treated in our depar
tment with the Nd:-YAG laser between 1989 and 1993. The average follow
-up was 23.8 months. The mean age of the patients was 65.7 years. The
patients were selected for organ-conserving treatment because of bilat
eral synchronous tumors (2 cases), a solitary renal unit (2 cases), re
nal insufficiency with high surgical risk (1 case) and high surgical r
isk alone (1 case). Two patients were treated with open tumor excision
and laser, two patients with ureteroscopic and percutaneous procedure
s one patient with percutaneous treatment and one patient with uretero
scopy. Two patients underwent nephroureterectomy; one of them died of
metastatic bladder cancer 9 months later. Local relapses were observed
in one patient who had been treated endoscopically. In a follow-up pe
riod of 6-36 months there were three patients who had no relapses. Thr
ee patients received intracavitary therapy. Kidney conserving procedur
es with the Nd:-YAG laser in patients with upper urinary tract tumors
should be reserved for highly selected cases.