Purpose: The procedure of axillofemoral bypass (AXF) grafting has gene
rally been used in the past for patients with serious contraindication
to certain reconstructive procedures involving the abdominal aorta. B
ecause some recent series have noted improved results, it has been sug
gested that the indications for this bypass may be extended. We review
ed our experience with AXE to identify which factors affect outcome, t
o determine whether recent results have improved, and to determine whe
ther an extension of the use of the procedure is justified by the obse
rved results. Method: One hundred fifty-three AXF, including 80 axillo
bifemoral bypasses and 73 axillounifemoral bypasses performed between
October 1974 and December 1992 were reviewed. Results: Three-year prim
ary and secondary patency rates for the entire group were 49.4% and 65
.7%. Primary patency was adversely affected (p < 0.05) by superficial
femoral artery occlusion, use of externally supported polytetrafluoroe
thylene, distal endarterectomy, distal anastomosis to the deep femoral
artery, and year of surgery after 1984, but not by use of unifemoral
or bifemoral outflow, side of graft origin, or concomitant distal proc
edure. The operative mortality rate of bypasses performed for claudica
tion and the limb salvage rate was 8.3% overall and 5.9% after 1984. L
imb salvage rates were 74.8% and 74.8% at 3 and 5 years. The patient s
urvival rate for all AXF was 55.8% and 39.2% at 3 and 5 years. AXF for
acute ischemia carried a high rate of mortality and limb loss. Conclu
sion: Bifemoral outflow external support, and more recent surgery were
not associated with improved patency rates. Our results do not suppor
t extended indications for AXF.