Jc. Hoehner et Am. Metcalf, DEVELOPMENT OF INVASIVE ADENOCARCINOMA FOLLOWING COLECTOMY WITH ILEOANAL ANASTOMOSIS FOR FAMILIAL POLYPOSIS-COLI - REPORT OF A CASE, Diseases of the colon & rectum, 37(8), 1994, pp. 824-828
PURPOSE: Proctocolectomy with ileoanal anastomosis has gained increasi
ng acceptance for the prophylactic treatment of patients with familial
polyposis coli. Longterm surveillance of the ileal pouch and the pouc
h-anal anastomosis has not been emphasized despite concern regarding r
etained rectal mucosa following the procedure. METHODS: A 34-year-old
patient with a strong family history of familial polyposis coli was tr
eated at 14 years of age by single-stage proctocolectomy with straight
ileoanal anastomosis. Follow-up proctoscopic examinations revealed de
velopment of adenomatous changes at the ileoanal anastomosis. RESULTS:
This report presents a patient with familial polyposis coli who devel
oped invasive adenocarcinoma at the ileoanal anastomosis 20 years afte
r proctocolectomy with ileoanal anastomosis. CONCLUSIONS: We stress th
e need for lifelong proctoscopic surveillance in patients with familia
l polyposis coli treated by proctocolectomy with ileoanal anastomosis.