HYALINE MATRIX MATERIAL IN HIGH-GRADE ENDOMETRIAL STROMAL SARCOMA DIAGNOSED BY FINE-NEEDLE ASPIRATION - CASE-REPORT

We present a case of a high-grade endometrial stromal sarcoma metastat ic to the abdomen with an unusual extracellular hyaline matrix materia l seen on fine needle aspiration biopsy, The patient was initially dia gnosed with a stage IIIA high-grade endometrial stromal sar-coma and h ad received four cycles of chemotherapy over the past year: She subseq uently developed an abdominal mass that consisted of discohesive small cells with scanty cytoplasm on fine needle aspiration. On the Diff-Qu ik-stained smears, metachromatic, extracellular hyaline material was i dentified. This appeared on the Papanicolaou-stained smear as cyanophi lic material and did riot react with reticulin stain. This case emphas izes the importance to the cytopathologist of including endometrial st romal sarcoma in the differential diagnosis of hyaline matrix material . (C) 1997 Wiley-Liss, Inc.