Perilymphatic fistula (PLF) remains one of the most challenging proble
ms in otological practice. Fifty-two consecutive patients (53 ears) wh
o underwent explorative tympanotomy for suspected PLF between 1985-199
2 were included in this study. The clinical picture, history, patients
' complaints and laboratory tests were analysed and compared with the
operative findings. The conclusions of our work are that the diagnosis
of PLF is based mostly on the clinical picture and a battery of labor
atory diagnostic tests, but no one test is truly diagnostic for PLF.