AGING AND GENETIC-CONTROL OF IMMUNE RESPONSIVENESS

Authors
DORIA G FRASCA D
Citation
G. Doria et D. Frasca, AGING AND GENETIC-CONTROL OF IMMUNE RESPONSIVENESS, Immunology letters, 40(3), 1994, pp. 231-233
Citations number
24
Categorie Soggetti
Immunology
Journal title
Immunology letters → ACNP
ISSN journal
01652478
Volume
40
Issue
3
Year of publication
1994
Pages
231 - 233
Database
ISI
SICI code
0165-2478(1994)40:3<231:AAGOIR>2.0.ZU;2-W
Abstract
Ageing is associated with a progressive decline of immune responsivene ss to exogenous antigens and increasing incidence of autoimmune phenom ena [1,2]. Many studies have been focused on the mechanisms of the imm unologic features of ageing. Alterations in cellular components of the immune system rather than in the extracellular milieu seem to account for most of the variations of immune competence in ageing [3].