PURPOSE: To assess the potential of non-contact holmium:YAG laser ther
mal keratoplasty to safely and effectively correct hyperopia up to +5.
00 diopters(D). METHODS: Non-contact laser thermal keratoplasty with a
holmium:YAG laser using energies ranging from 215 to 255 mJ with 6, 7
, and 8-mm ablation zone diameters, was applied to 57 sighted eyes of
42 hyperopic patients in a controlled study. All patients were followe
d for 15 months after surgery RESULTS: Preoperative spectacle-correcte
d visual acuity returned to baseline levels from 2 to 6 weeks after tr
eatment. Regression of effect was evident in all eyes, and after 15 mo
nths was total in 18 eyes (31.5%). The mean cycloplegic refraction bef
ore surgery was +3.80 +/- 0.22 D (range, +1.50 to +5.00 D); after surg
ery, it was +1.40 +/- 0.12 at 3 months, +1.69 +/- 0.19 D at 6 to 8 mon
ths, and +1.73 +/- 0.16 D at 15 months. At the end of the study, 41 ey
es (71.9%) had an uncorrected visual acuity of 20/40 or better. Thirty
-two eyes (58.8%) were within +/- 1.00 D of the intended refraction. P
atient age and central pachymetric values were significantly correlate
d with regression (ANOVA, p less than .005). CONCLUSION: Regression of
initial effect can be large with non-contact holmium:YAG laser therma
l keratoplasty. We think the technique works best up to +3.00 D in old
er individuals with central corneal thickness less than 525 mu m. Algo
rithms to improve the final results should include an initial calculat
ed overcorrection adjusted on variables that influence regression such
as patient age and corneal thickness.