A 34-year-old man with AIDS was admitted to the hospital with a one-we
ek history of cough, chest pain, and fever. Radiography revealed a cav
itating left upper lobe lesion. Two weeks later he developed a headach
e associated with a contrast enhancing lesion in the right parietal lo
be. The patient had a progressive downhill course, developing atrioven
tricular block and hypernatremia. Neuro-ophthalmologically, there was
a mild facial droop, ''hand motions'' vision with presumed bilateral c
ytomegalic inclusion retinitis, and signs of a mesencephalic syndrome,
including lid retraction. Discussions center on the differential diag
nosis of the central nervous system disease and the obligative recomme
ndations the neuro-ophthalmologist must be willing to make.