Since first described in 1883 by Fournier only 420 cases of Fournier's
gangrene have been published worldwide during the last 100 years. The
anatomic association between the fascies of penis, scrotum, perineum,
groin and gluteal favors the fast spread of tissue necrosis. We repor
t two cases in which the penis, scrotum and a great part of the trunk
and extremities were affected. Extensive debridement, including remova
l of the scrotum, and antibiotic treatment permitted us to get rid of
the symptoms. Reconstruction of the skin defects was done in a second
step by applying mesh grafts. The histological findings correspond to
those found in cases of necrotizing fasciitis. The basic difference be
tween these two illnesses is their localization. While Fournier's gang
rene, as a special form, is localized primarily in the anogenital area
, fasciitis may arise in all locations. For successful treatment of Fo
urnier's gangrene speedy radical debridement and local application of
antibiotics to cover the entire area are required.