THE ANTIOXIDANT ENZYMES ACTIVITY IN THE CONDITIONS OF SYSTEMIC HYPERSILICEMIA

Authors
NAJDA J GOSS M GMINSKI J WEGLARZ L SIEMIANOWICZ K OLSZOWY Z
Citation
J. Najda et al., THE ANTIOXIDANT ENZYMES ACTIVITY IN THE CONDITIONS OF SYSTEMIC HYPERSILICEMIA, Biological trace element research, 42(1), 1994, pp. 63-70
Citations number
30
Categorie Soggetti
Biology
Journal title
Biological trace element research → ACNP
ISSN journal
01634984
Volume
42
Issue
1
Year of publication
1994
Pages
63 - 70
Database
ISI
SICI code
0163-4984(1994)42:1<63:TAEAIT>2.0.ZU;2-1
Abstract
The effect of an excessive inorganic silicon oral intake on the activi ty of basic antioxidant enzymes was studied in rats. Activities of sup eroxide dismutase, catalase, and glutathione peroxidase were measured in liver and kidney tissues of animals receiving per os sodium metasil icate nonahydrate (Na2SiO3.9H(2)O) (Sigma, [St. Louis, MO]) dissolved in their drinking water. A decrease of the activity of all the studied enzymes was found in the samples derived from the experimental group. The results obtained indicate the free oxygen radicals participation in the potential pathologic events in the conditions of systemic hyper silicemia.