Fibulin-1 is a calcium-binding glycoprotein present in the extracellul
ar matrix and in the serum. The gene coding for fibulin-1 (FBLN1) was
located by in situ hybridization of H-3-labeled cDNA probes to human a
nd mouse metaphase chromosomes. The gene was assigned to the q13.2-q13
.3 region of human chromesome 22 and to the E-F band of mouse chromoso
me 15. This finding extends the evolutionary conservation between huma
n chromosome 22 and mouse chromesome 15. (C) 1994 Academic Press, Inc.