Two new polyether squalene derivatives, thyrsenol A 2 and thyrsenol B
3, have been isolated from the red alga Laurencia viridis. Their struc
tures, which possess all unusual enol-ether moiety. were determined th
rough the interpretation of 2D-NMR spectral data. The relative stereoc
hemistry is proposed on tile basis of ROESY and NOEDIFF data. Their cy
totoxic activities were evaluated. (C) 1997 Published by Elsevier Scie
nce Ltd.