Vision loss during a centrifuge run is an expected occurrence given th
e G-profile, physical fitness of the subject, expected visual endpoint
[central light loss (CLL) or peripheral light loss (PLL)] of the expe
rimental protocol, and the cyclic nature of the anti-G straining maneu
ver (AGSM). During a relatively low level G exposure, a subject experi
enced a unilateral loss of vision that did not resolve spontaneously u
pon removal of the G load. An extensive medical workup did not reveal
any medical explanation for the vision loss.