HALOGENATION USING N-HALOGENOCOMPOUNDS .2. ACID-CATALYZED BROMINATIONOF AROMATIC-COMPOUNDS WITH 1,3-DIBROMO-5,5-DIMETHYLHYDANTOIN

Authors
EGUCHI H KAWAGUCHI H YOSHINAGA S NISHIDA A NISHIGUCHI T FUJISAKI S
Citation
H. Eguchi et al., HALOGENATION USING N-HALOGENOCOMPOUNDS .2. ACID-CATALYZED BROMINATIONOF AROMATIC-COMPOUNDS WITH 1,3-DIBROMO-5,5-DIMETHYLHYDANTOIN, Bulletin of the Chemical Society of Japan, 67(7), 1994, pp. 1918-1921
Citations number
21
Categorie Soggetti
Chemistry
Journal title
Bulletin of the Chemical Society of Japan → ACNP
ISSN journal
00092673
Volume
67
Issue
7
Year of publication
1994
Pages
1918 - 1921
Database
ISI
SICI code
0009-2673(1994)67:7<1918:HUN.AB>2.0.ZU;2-U
Abstract
Ring bromination of aromatic compounds using 1.3-dibromo-5,5-dimethylh ydantoin in dichloromethane is promoted by the addition of strong acid s. Both organic and inorganic acids whose pK(a) values are lower than -2 showed the promoting effect. This acid-catalyzed bromination is bot h practical and effective, even for aromatics having electron-withdraw ing substituents.