CRYSTAL-STRUCTURE AND CONFORMATION OF N-(T-BUTOXYCARBONYL)-L-ALANYL-S-BENZYL-L-CYSTEINE METHYL-ESTER

Authors
SUKUMAR N PONNUSWAMY MN JAYAKUMAR R
Citation
N. Sukumar et al., CRYSTAL-STRUCTURE AND CONFORMATION OF N-(T-BUTOXYCARBONYL)-L-ALANYL-S-BENZYL-L-CYSTEINE METHYL-ESTER, Bulletin of the Chemical Society of Japan, 67(7), 1994, pp. 1976-1979
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Bulletin of the Chemical Society of Japan → ACNP
ISSN journal
00092673
Volume
67
Issue
7
Year of publication
1994
Pages
1976 - 1979
Database
ISI
SICI code
0009-2673(1994)67:7<1976:CACON>2.0.ZU;2-O
Abstract
The dipeptide, N-(t-butoxycarbonyl)-L-alanyl-S-benzyl-L-cysteine methy l ester (Boc-Ala-Cys(Bzl)OMe) has been crystallized in orthorhomic spa ce group P2(1)2(1)2(1) with cell dimensions of a = 9.565(1), b = 43.28 2(1), and c = 5.096(1) angstrom. The structure was determined by direc t methods and refined to an R-factor of 0.049. The molecules are packe d in a parallel-pleated sheet arrangement and stabilized by N-H...O hy drogen bonds.