Sm. Gersten, THE AUTOMORPHISM GROUP OF A FREE GROUP IS NOT A CAT(0) GROUP, Proceedings of the American Mathematical Society, 121(4), 1994, pp. 999-1002
If F is a finitely generated free group, then the group Aut(F), if ran
k(F) greater-than-or-equal-to 3, and Out(F) , if rank(F) greater-than-
or-equal-to 4, are not isomorphic to a sub-group of a group which acts
properly discontinuously and cocompactly on a 1-connected geodesic me
tric space satisfying Gromov's condition CAT(0).