N. Kato et al., TREATMENT OF ACUTE AORTIC DISSECTIONS WITH EXPANDABLE METALLIC STENTS- EXPERIMENTAL-STUDY, Journal of vascular and interventional radiology, 5(3), 1994, pp. 417-423
PURPOSE: This experimental study was designed to evaluate the effectiv
eness of metallic stents for the treatment of acute aortic dissection.
MATERIALS AND METHODS: Thoracic aortic dissections were created in 14
mongrel dogs. Aortography performed immediately after creation of dis
sections showed two types of aortic dissections: rapid flow in the fal
se lumen (group 1) and slow flow in the false lumen (group 2). Each gr
oup consisted of seven dogs. For each group, expandable metallic Giant
urco stents were placed in five dogs and two dogs were used as control
s. RESULTS: A week later, false lumina were patent in all dogs in grou
p 1 and thrombosed in all dogs in group 2. In group 1, the mean diamet
er of the true lumina was considerably enlarged from 5.9 mm +/- 1.6 to
9.9 mm +/- 2.8 and that of the false lumina significantly diminished
from 9.1 mm +/- 1.3 to 5.2 mm +/- 2.3 (P < .05) after stent placement.
In group 2, the true lumina were significantly dilated (5.2 mm +/- 2.
3 vs 12.3 mm +/- 3. 1, P < .05) and the false lumina disappeared compl
etely (9.2 mm +/- 3.3 vs 0.0 mm, P < .0 1). Furthermore, the two contr
ol dogs in group 2 died of visceral ischemia due to the compression of
the true lumen by the thrombosed false lumina, but the dogs with sten
ts showed no symptoms of the visceral ischemia. CONCLUSION: Expandable
metallic stents are not effective in obliterating the false lumen in
acute aortic dissection but may be useful in maintaining the blood flo
w in the true lumen and avoiding visceral ischemia.