R. Hughes et al., UPPER AIRWAY EDEMA AFTER CAROTID ENDARTERECTOMY - THE EFFECT OF STEROID-ADMINISTRATION, Anesthesia and analgesia, 84(3), 1997, pp. 475-478
The objective of this study was to evaluate the effect of preoperative
steroid administration on the site and extent of upper airway edema a
fter carotid endarterectomy. The design was a randomized, prospective,
double-blind controlled trial. Thirty-eight patients undergoing elect
ive carotid endarterectomy (17 patients were in the steroid-treated gr
oup and 21 in the control group) were administered either 16 mg of dex
amethasone or saline placebo prior to surgery. Computed tomograms (CT)
scans of the neck were performed on the patients preoperatively and 2
4 h postoperatively. Measurements were taken from the CT scans of the
airway transverse and anterior-posterior diameters at the levels of th
e hyoid bone, arytenoid cartilage, and cricoid cartilage. No postopera
tive neck hematomas were seen on the CT scans. Although neck edema was
observed postoperatively, the upper airway dimensions were not statis
tically significantly different between the steroid and the control gr
oups. We conclude that steroid administration immediately preoperative
ly has no clinical effect in reducing edema formation in the upper air
way postcarotid endarterectomy.