Wm. Splinter et L. Komocar, NITROUS-OXIDE DOES NOT INCREASE VOMITING AFTER DENTAL RESTORATIONS INCHILDREN, Anesthesia and analgesia, 84(3), 1997, pp. 506-508
The effect of nitrous oxide on postoperative vomiting was evaluated in
330 children who underwent outpatient dental restorations. There were
two groups in this single-blind, randomized, controlled study. One gr
oup received nitrous oxide during their anesthetic, while the non-nitr
ous oxide group did not receive nitrous oxide at any time. Anesthesia
was induced by inhalation with halothane or with propofol intravenousl
y. The incidence of vomiting for 24 h after surgery was recorded. Over
all, the incidence of vomiting was similar, with 30% of the control pa
tients and 35% of the nitrous-treated patients vomiting after their an
esthetic. However, in-hospital vomiting was less in the control group:
15% vs 24%, control versus nitrous oxide, P = 0.03. In conclusion, ni
trous oxide does not alter postoperative vomiting after halothane anae
sthesia for dental restorations in children.