AMEBIC-ABSCESS OF THE SPLEEN COMPLICATED BY METRONIDAZOLE-INDUCED NEUROTOXICITY - CASE-REPORT

Authors
LAWFORD R SORRELL TC
Citation
R. Lawford et Tc. Sorrell, AMEBIC-ABSCESS OF THE SPLEEN COMPLICATED BY METRONIDAZOLE-INDUCED NEUROTOXICITY - CASE-REPORT, Clinical infectious diseases, 19(2), 1994, pp. 346-348
Citations number
19
Categorie Soggetti
Microbiology,Immunology,"Infectious Diseases
Journal title
Clinical infectious diseases → ACNP
ISSN journal
10584838
Volume
19
Issue
2
Year of publication
1994
Pages
346 - 348
Database
ISI
SICI code
1058-4838(1994)19:2<346:AOTSCB>2.0.ZU;2-7
Abstract
We describe a patient with a liver abscess due to Entamoeba histolytic a, in whom metronidazole therapy (total dose, 21 g over 14 days) was c omplicated by reversible deafness, tinnitus, and ataxia and who relaps ed 5 months later with a splenic abscess. Two courses of tinidazole (t he second in combination with percutaneous aspiration of the abscess) were required to achieve cure.