H. Kaga et al., NEW ACCESS TO CONJUGATED DIENAMIDES AND ENAMIDES - SYNTHESIS OF DEHYDROPIPERNONALINE, PIPERNONALINE AND RELATED BIOLOGICALLY-ACTIVE AMIDES, Synlett, (8), 1994, pp. 607-608
A new method for the synthesis of conjugated dien- and enamides by pal
lladium-catalyzed coupling reaction of (E)-beta-bromo-acrylamides with
alkenyl- and alkylboronates is reported. This procedure provided some
biologically active, naturally occurring unsaturated amides, such as
dehydropipemonaline, pipernonaline and other related alkaloids, in one
-pot.