A discussion is presented, from the point of view of an empiricist, of
a number of topics which are important to our current understanding o
f interstellar extinction. These include the misuse of mean reddening
laws, the origins of differential reddening, and the question of varia
tions in R, the ratio of total-to-selective extinction. The effectiven
ess of detailed reddening studies -including reddening line determinat
ions, dereddening of individual stars, and variable-extinction analyse
s- of open clusters is demonstrated, with particular reference to R-de
terminations for Tr 37 (R = 2.83 +/- 0.12), Sco-Oph (R = 3.34 +/- 0.08
), and NGC 6611 (R = 2.99 +/- 0.08, with some evidence that R = 4.42 /- 0.10 in the dusty northern region) and to the discovery of new evid
ence for circumstellar extinction. It is demonstrated that the observa
ble variations in R from 2.8 and 3.0 to 3.3 in these cluster fields ar
e tied to comparable variations in the reddening line slope E(U - B)/E
(B - V) for these lines of sight (X = 0.80, 0.74, and 0.63, respective
ly), but that the evidence does not support the arguments from IR, stu
dies for anomalous extinction with values of R approximately 4 or more
. The question is raised as to whether or not the highly-reddened star
s in Sco-Oph serve as proper standards for studies of extinction law v
ariations.