A retrospective review of 8 trigeminal nerve tumors centered in the la
teral skull base was carried out. Clinical manifestations, radiographi
c features, and outcome of management are detailed. Six patients in th
is series presented for primary surgery, and 2 patients had prior surg
ical interventions with incomplete resections. Surgical exposure via t
he infratemporal fossa (ITF) approaches resulted in complete tumor ext
irpation in all but 1 of the reoperated cases. Limited postoperative c
ranial neuropathies and the lack of intracranial complications are par
ticularly notable in this series. A mean follow-up of 3 years revealed
no evidence of recurrent disease. In the case of incomplete resection
, there appears to be no appreciable growth of the small tumor remnant
in the region of the cavernous sinus after 5 years. Trigeminal tumors
of the lateral skull base with intracranial components below the leve
l of the posterior clinoid process are ideally suited for the ITF tech
niques. The importance of securing the petrous carotid artery through
a wide exposure is emphasized.