C. Thomas et Jp. Leonetti, PAPILLARY (MALIGNANT) MENINGIOMA OF THE FORAMEN MAGNUM PRESENTING AS A POSTERIOR NECK MASS, Skull base surgery, 4(3), 1994, pp. 164-168
Meningiomas and neurofibromas are the most common extramedullary tumor
s in the region of the foramen magnum. The clinical symptoms are varia
ble, including headache, occipitocervical pain, and hoarseness. Neurol
ogical symptoms are present only in 40% of cases. The age group ranges
from 4 to 56 years. A number of patients are misdiagnosed as multiple
sclerosis, syringomyelia, and cervical disc disease. The overall inci
dence of these tumors vary from 1.6 to 2.4%. The majority of meningiom
as are histologically benign. Papillary (malignant) meningiomas are ev
en rarer in this location. The present report is that of a 46-year-old
man who developed a painless mass in the nape of his neck, without an
y neurological symptoms. Following initial biopsy at another hospital,
a definitive resection was undertaken at Loyola University Medical Ce
nter. The diagnosis of a malignant meningioma was made after extensive
immunohistochemical and electron microscopic studies. The patient dev
eloped a positive cervical lymph node 1 year later, which was excised
and showed identical histopathologic features