Ak. Srivastava et al., A FACILE SYNTHESIS OF A THYL-3-PHENYL-4-(P-PYRROLIDINOETHOXYPHENYL)CHROMAN, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 33(8), 1994, pp. 773-774
cis-Centchroman (6) on treatment with hydrazine hydrate, ethylene glyc
ol and potassium hydroxide under oxygen-free nitrogen atmosphere at 23
0-240-degrees-C, undergoes both dealkylation and isomerisation reactio
ns giving rise to desmethylcentchroman (1) and 3,4-trans-7-hydroxy-2,
2-dimethyl-4-(p-hydroxyphenyl)chroman (2) in almost equal proportions.