PUTATIVE METABOLITES OF 8-AMINOQUINOLINE ANTIMALARIALS - SYNTHESIS AND TISSUE SCHIZONTOCIDAL ACTIVITY OF 8-SUBSTITUTED-AMINO-5,6-DIHYDROXY 5-HYDROXY-6-METHOXY-4-METHYLQUINOLINES AND 6-ALKOXY-5,8-QUINOLINEQUINONES

Authors
JAIN R GUPTA RC ANAND N
Citation
R. Jain et al., PUTATIVE METABOLITES OF 8-AMINOQUINOLINE ANTIMALARIALS - SYNTHESIS AND TISSUE SCHIZONTOCIDAL ACTIVITY OF 8-SUBSTITUTED-AMINO-5,6-DIHYDROXY 5-HYDROXY-6-METHOXY-4-METHYLQUINOLINES AND 6-ALKOXY-5,8-QUINOLINEQUINONES, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 33(8), 1994, pp. 792-794
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
33
Issue
8
Year of publication
1994
Pages
792 - 794
Database
ISI
SICI code
0376-4699(1994)33:8<792:PMO8A->2.0.ZU;2-M
Abstract
-di-methoxy/5-hydroxy-6-methoxy-4-methylquinolines (2a-d) and 6-alkoxy -5,8-quinolinequinones (4a-d) have been synthesised and evaluated for their radical curative antimalarial activity against Plasmodium cynomo lgi in the rhesus monkeys. All the compounds showed no significant act ivity.