GASTROINTESTINAL ABSORPTION OF AMERICIUM IN RATS - EFFECT OF CITRATE CONCENTRATION

Authors
INABA J ISHIGURE N OGHISO Y SATO H
Citation
J. Inaba et al., GASTROINTESTINAL ABSORPTION OF AMERICIUM IN RATS - EFFECT OF CITRATE CONCENTRATION, Radiation protection dosimetry, 53(1-4), 1994, pp. 335-337
Citations number
NO
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging","Nuclear Sciences & Tecnology
Journal title
Radiation protection dosimetry → ACNP
ISSN journal
01448420
Volume
53
Issue
1-4
Year of publication
1994
Pages
335 - 337
Database
ISI
SICI code
0144-8420(1994)53:1-4<335:GAOAIR>2.0.ZU;2-N
Abstract
The gastrointestinal absorption of Am-241 was studied in relation to t he amount of sodium citrate administered with it. Fasted Wistar strain female rats received Am-241 orally in sodium citrate solution of vari ous concentrations and 5 days after administration animals were sacrif iced and the retention and distribution of Am-241 was studied. The res ults indicated that the f1 value was very high at about 10% of adminis tered activity when Am-241 was given to fasted rats with a large amoun t of sodium citrate.