METHYLGLYOXAL AND CELL VIABILITY

Authors
BRAUN L GARZO T RIBA P MANDL J KALAPOS MP
Citation
L. Braun et al., METHYLGLYOXAL AND CELL VIABILITY, International Journal of Biochemistry, 26(8), 1994, pp. 987-990
Citations number
16
Categorie Soggetti
Biology
Journal title
International Journal of Biochemistry → ACNP
ISSN journal
0020711X
Volume
26
Issue
8
Year of publication
1994
Pages
987 - 990
Database
ISI
SICI code
0020-711X(1994)26:8<987:MACV>2.0.ZU;2-Z
Abstract
1. Methylglyoxal by depleting glutathione stores increased Trypan-blue uptake by the cells incubated in glucose, pyruvate and amino acids fr ee medium. 2. Only a transient fall of glutathione concentration witho ut any effect on cell viability was caused by methylglyoxal when the m edium was supplemented with above-mentioned compounds. 3. The role of gamma-glutamyl-transpeptidase is discussed.