H. Takeshita et al., DETECTION OF DEOXYRIBONUCLEASE-I AND DEOXYRIBONUCLEASE-II (DNASE-I AND DNASE-II) ACTIVITIES IN REPRODUCTIVE-ORGANS OF MALE RABBITS, International Journal of Biochemistry, 26(8), 1994, pp. 1025-1031
1. Deoxyribonucleases (DNases) I and II activities in 13 different org
ans and body fluids from healthy male rabbits were measured using the
single radial enzyme diffusion method. 2. We now show that testis, epi
didymis, ampulla, seminal vesicle, vesicular gland, prostate, and seme
n have both of the DNases I and II activities, whereas spermatozoa do
not. 3. DNase I activities were highest in epididymis and seminal vesi
cle, whereas DNase II activities were highest in epididymis and prosta
te among the reproductive organs. 4. The presence of these two enzyme
activities outside the digestive system suggests that they have anothe
r biological function in addition to their digestive roles.