ORIGIN, MATURATION AND ANTIGEN-PRESENTING FUNCTION OF DENDRITIC CELLS

Authors
CELLA M SALLUSTO F LANZAVECCHIA A
Citation
M. Cella et al., ORIGIN, MATURATION AND ANTIGEN-PRESENTING FUNCTION OF DENDRITIC CELLS, Current opinion in immunology, 9(1), 1997, pp. 10-16
Citations number
75
Categorie Soggetti
Immunology
Journal title
Current opinion in immunology → ACNP
ISSN journal
09527915
Volume
9
Issue
1
Year of publication
1997
Pages
10 - 16
Database
ISI
SICI code
0952-7915(1997)9:1<10:OMAAFO>2.0.ZU;2-A
Abstract
Dendritic cells are cells specialized for antigen capture, migration a nd T cell stimulation. Recent advances have been made in understanding their origin, their heterogeneity, the mechanism of antigen uptake, a nd the signals that induce their migration and maturation into immunos timulatory antigen-presenting cells. Dendritic cells represent the nat ural adjuvants for T cell responses and their therapeutic exploitation in the near future is foreseen.