EVALUATION OF 3RD-GENERATION ASSAYS FOR DETECTION OF ANTI-HEPATITIS-CVIRUS (HCV) ANTIBODIES AND COMPARISON WITH PRESENCE OF HCV RNA IN BLOOD-DONORS REACTIVE TO C100-3 ANTIGEN

Authors
LAVANCHY D MAYERAT C MOREL B SCHNEIDER P ZUFFEREY C GONVERS JJ PECOUD A FREI PC
Citation
D. Lavanchy et al., EVALUATION OF 3RD-GENERATION ASSAYS FOR DETECTION OF ANTI-HEPATITIS-CVIRUS (HCV) ANTIBODIES AND COMPARISON WITH PRESENCE OF HCV RNA IN BLOOD-DONORS REACTIVE TO C100-3 ANTIGEN, Journal of clinical microbiology, 32(9), 1994, pp. 2272-2275
Citations number
24
Categorie Soggetti
Microbiology
Journal title
Journal of clinical microbiology → ACNP
ISSN journal
00951137
Volume
32
Issue
9
Year of publication
1994
Pages
2272 - 2275
Database
ISI
SICI code
0095-1137(1994)32:9<2272:EO3AFD>2.0.ZU;2-G
Abstract
We tested serum samples from blood donors by using first-, second-, an d third-generation enzyme immunoassays or recombinant immunoblot assay s. Second- and third-generation assays gave comparable results. Circul ating hepatitis C virus RNA was found in a high proportion of reactive samples. A lack of reactivity or low-level reactivity predicted the a bsence of hepatitis C virus RNA in 100% of the cases.