Laparoscopic splenectomy was performed on eight patients with idiopath
ic thrombocytopenic purpura refractory to medical treatment. Preoperat
ive infusion of immunoglobulin G gamma-globulin was used to boose the
platelet count. Accessory spleens were sought by preoperative computed
tomography and peroperative examination of the usual anatomical locat
ions. Seven patients underwent successful laparoscopic splenectomy, wi
th a mean postoperative stay of 3.6 days. One patient with an accessor
y spleen detected before operation but not during laparoscopy required
conversion to open surgery for control of haemorrhage from the spleni
c hilum. Another patient had a transient pancreatic fistula. Laparosco
pic splenectomy is feasible and safe in patients with idiopathic throm
bocytopenic purpura. Long-term results require evaluation as detection
of accessory spleens can prove difficult during laparoscopy.