Va. Kraevskii et al., APPLICATION OF LOW-DENSITY AGAROSE-GEL ELECTROPHORESIS IN STUDIES OF CHROMATIN CONDENSATION, Molecular biology, 28(1), 1994, pp. 50-54
Low-density agarose gel electrophoresis was employed to study conforma
tional changes in supranucleosome chromatin structure under the influe
nce of variable ionic environment. The original method proposed in the
paper is both simple and accurate. The results obtained are in accord
with the data obtained by conventional methods. The method could be u
sed as an alternative to ultracentrifugation in the studies of chromat
in condensation.