Background: Currently, donors may arrive at blood collection sites wit
hout prior knowledge of eligibility and deferral criteria. Study Desig
n and Methods: The effects of distributing newly developed recruitment
brochures 2 weeks in advance of blood drives and the provision of bro
chures on temporary deferral at the taking of health history were exam
ined in four southeastern regional blood collection centers. Twenty-fo
ur similar pairs of worksites, with employee-only recruitment, were ra
ndomly assigned to a control (C) or experimental (E) group. Informatio
n about sponsor recruitment strategies, worksite factors, and first-ti
me, repeat, and temporarily deferred donors was obtained at three coll
ection drives per site over a 1-year period. Drive 1 was used as a bas
eline. Two weeks before Drives 2 and 3, the recruitment brochures were
distributed to all Group E employees, with temporary deferral brochur
es provided as needed when the health history was taken. Results: No s
ignificant differences between groups or drives were found in the tota
l percentage of employees recruited or returning as a result of recrui
tment or deferral brochure distribution (Wilcoxon's signed rank test a
nd t test). Substantiating previous observations by donor recruiters,
the study results showed decreased donations during vacation periods a
nd busier times at the workplace. Loudspeaker announcements led to dec
reased donations; increased donations followed special appeals in rela
tion to a specific patient, an accident, or a natural disaster. Conclu
sion: The brochures may have encouraged previous donors to return, but
their use did not significantly increase the recruitment of new donor
s or the return of temporarily deferred donors.