The purpose of this longitudinal investigation was to study the dentof
acial changes occurring between 25 and 46 years of age in an untreated
normal sample. Measurements were made from cephalograms and dental ca
sts available on 15 women and 15 men at age 25 and 46 years. The findi
ngs indicate that females exhibited significant increases in all skele
tal facial linear dimensions, a decrease in cranial base angle and man
dibular prominence, an increase in skeletal convexity and facial diver
gence. Most of these changes were of relatively small magnitude. Over
the span of the study, significant crowding occurred in the mandibular
arch. Males exhibited similar significant increases in all skeletal l
inear dimensions, a decrease in cranial base angle, and increases in m
axillary skeletal prominence and skeletal convexity. Increased crowdin
g with age was seen in both maxillary and mandibular arches. In conclu
sion, the findings indicate that a clinically significant increase in
tooth size-arch length discrepancies occurred between 25 and 46 years
of age. These changes should be considered as part of the normal ''mat
urational'' process. Furthermore, the relative changes in the position
of the lips, nose, and chin, cause the lips to appear more retrusive
at 46 years of age. These changes should be taken into consideration w
hen orthodontists are considering various treatment and retention opti
ons for their adult patients.