K. Konstantopoulos et al., BACTEROIDES-FRAGILIS ARTHRITIS IN A SICKLE CELL-THALASSEMIA PATIENT, Scandinavian journal of infectious diseases, 26(4), 1994, pp. 495-497
Anaerobic arthritis due to Bacteroides fragilis was diagnosed in a 33-
year-old patient with prolonged fever suffering from sickle cell/thala
ssaemia. The causative agent was isolated from blood and purulent syno
vial fluid from both knee joints. A combination of chloramphenicol plu
s metronidazole treatment proved effective. Anaerobic arthritis has no
t previously been described in patients with sickle cell disease, and
may reflect the well-known susceptibility of these patients to pathoge
ns.