As part of an open clinical trial currently underway at the Max Planck
Institute of Psychiatry in Munich, the feasibility of behavioral fami
ly management (Falloon et al. 1984) for schizophrenia in combination w
ith two different neuroleptic medication strategies was investigated.
The treatment approaches were psychoeducational family management with
a standard dose or with targeted medication. In this article the foll
owing questions were addressed: (1) What proportion of the total schiz
ophrenia population admitted as inpatients might be eligible for psych
oeducational family treatment (assessment based on n = 411 over a 33-m
onth period)? (2) How representative of this population are the patien
ts who were randomized to the experimental groups? (3) How many patien
ts dropped out of treatment after entering the trial? The results show
that about 60 percent (247) of the patients were eligible for a psych
o-educational treatment approach. Of these, 34 percent (85) participat
ed in the trial and were randomized to the treatments. Only 4 percent
of the relatives but 20 percent of the patients refused to take part i
n the study. The 85 trial patients did not differ from the total eligi
ble on the numerous socioeconomic and symptom variables assessed. The
treatment dropout rate was 11 percent. Those patients who accepted tre
atment did not differ from those patients who dropped out on socioecon
omic or illness variables. The results indicate that early identificat
ion of dropouts is not possible at least with the methods used in this
study.