G. Friedel et al., VIDEO-ASSISTED THORACOSCOPIC PLEURECTOMY AS THERAPY FOR RECURRING MALIGNANT PLEURAL EFFUSION, Minimally invasive therapy, 3(3), 1994, pp. 169-172
Recurring malignant pleural effusion is a common problem with carcinom
as invading the pleural surface. Associated symptoms like dyspnoea, co
ugh, and arrhythmia considerably limit the patient's remaining quality
of life. Numerous methods have been advocated to induce pleurodesis.
The various forms of treatment range from chest tube drainage over ins
tillations of sclerosing substances like tetracyclines, cytostatics, a
nd talc to pleurectomy. None of these treatments, however, so far fulf
ills the demands for maximum effectiveness with a low rate of recurren
ce and morbidity. With the introduction of video-assisted thoracoscopi
c pleurectomy, a method with a low rate of recurrence and morbidity is
now at our disposal. During the last 18 months 21 patients with vario
us primary tumours have undergone pleurectomy for pleural carcinomatos
is in our hospital. All patients had previously been treated by other
methods. In all cases of secondary pleural carcinomatosis a complete p
arietal pleurectomy was possible. The intra-operative loss of blood wa
s low, with an average of 370 ml. Intra- or post-operative complicatio
ns did not occur. The mean duration of chest tube drainage was 7 d and
the post-operative hospital stay 12 d. During a period of 18 months w
e have recorded one recurrence requiring no further treatment. These r
esults show that video-assisted thoracoscopic pleurectomy should be un
dertaken early when other non-invasive methods have failed.