F. Dire et al., SURGICAL STAGING FOR EPITHELIAL OVARIAN-TUMORS OF LOW MALIGNANT POTENTIAL, International journal of gynecological cancer, 4(5), 1994, pp. 310-314
From january 1975 to December 1991, 34 patients with a diagnosis of ep
ithelial ovarian tumors of low malignant potential (LMP) were admitted
to the Istituto Nazionale Tumori of Milan. Eighteen of them (group 1)
underwent complete staging laparotomy and retroperitoneal para-aortic
and pelvic lymphadenectomy, as for ovarian cancer. In the remaining 1
6 cases (group 2), the surgical treatment ranged from unilateral oopho
rectomy to incomplete staging procedure. In group 1, nine patients (50
%) were found to have retroperitoneal nodal involvement. In group 2, a
ll patients had stage I disease. Patients were followed up for 20-222
months (mean 108, median 86). There were two recurrences in group 2 (a
fter 5 years) and none in group 1 (NS). Currently all patients are ali
ve and disease free. Nine of 18 group 1 patients were upstaged to stag
e III on the basis of lymph node involvement only. However, at least i
n this retrospective series, lymph node metastases did not affect prog
nosis or survival.