Six patients with vaginal sarcoma are reported here. This clinicopatho
logic review confirms the poor prognosis of this disease. However, the
re were three 5-year survivors, all of whom had early stage disease an
d low to intermediate grade tumors. Apart from tumor grade, stage was
of prognostic importance. Late recurrences at 5 and 21 years were note
d in two of the three 5-year survivors. Neither chemotherapy nor radio
therapy were of use in the treatment of late stage or recurrent diseas
e.