CONVENIENT ONE-POT METHOD FOR FORMYLATION OF AMINES AND ALCOHOLS USING FORMIC-ACID AND 1,1'-OXALYLDIIMIDAZOLE

Authors
KITAGAWA T ARITA J NAGAHATA A
Citation
T. Kitagawa et al., CONVENIENT ONE-POT METHOD FOR FORMYLATION OF AMINES AND ALCOHOLS USING FORMIC-ACID AND 1,1'-OXALYLDIIMIDAZOLE, Chemical and Pharmaceutical Bulletin, 42(8), 1994, pp. 1655-1657
Citations number
34
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Chemical and Pharmaceutical Bulletin → ACNP
ISSN journal
00092363
Volume
42
Issue
8
Year of publication
1994
Pages
1655 - 1657
Database
ISI
SICI code
0009-2363(1994)42:8<1655:COMFFO>2.0.ZU;2-H
Abstract
1,1'-Oxalyldiimidazole (7) reacts with formic acid (8) in acetonitrile at room temperature to give N-formylimidazole (5), which promptly und ergoes aminolysis and alcoholysis to yield formamides (2) or formates (4).