PATHWAYS OF CYSTEINE METABOLISM IN MND ALS

Authors
PEAN A STEVENTON GB WARING RH FOSTER H STURMAN S WILLIAMS AC
Citation
A. Pean et al., PATHWAYS OF CYSTEINE METABOLISM IN MND ALS, Journal of the neurological sciences, 124, 1994, pp. 59-61
Citations number
15
Categorie Soggetti
Neurosciences
Journal title
Journal of the neurological sciences → ACNP
ISSN journal
0022510X
Volume
124
Year of publication
1994
Supplement
S
Pages
59 - 61
Database
ISI
SICI code
0022-510X(1994)124:<59:POCMIM>2.0.ZU;2-K
Abstract
Analysis of plasma from MND/ALS patients has shown no significant diff erences in metabolism of cysteine derivatives, although a sub-set of t he population has raised glutamate values. Cysteine dioxygenase was fo und to have reduced activity in vitro, consistent with previous findin gs of a high plasma cysteine/sulphate ratio.