We report the clinical and instrumental data, including the endomyocar
dial biopsy findings, of six young athletes presenting with minor arrh
ythmias and/or echocardiographic abnormalities. In one of them, a left
ventricular dilation with moderate depression of the systolic functio
n had been attributed to an athlete's heart. A diagnosis of arrhythmog
enic right ventricular dysplasia had been made in three others, one wi
th right ventricular dilation and apical hypokinesia, and two with ven
tricular arrhythmias with QRS morphology of left bundle branch block.
A myocarditis could be unequivocally established in four athletes (two
with and two without fibrosis). In the remaining two, with a clinical
history strongly suggesting a previously acute myocarditis, the endom
yocardial biopsy specimen revealed a nonspecific fibrosis compatible b
ut not definitely pathognomonic of a healed myocarditis. Our report su
ggests that a myocarditis may be a cause of minor rhythm disturbances
and/or echocardiographic abnormalities in athletes. A prevalent locali
zation of the inflammatory process in the right ventricle with or with
out the occurrence of ventricular arrhythmias with left bundle branch
block morphology can mimic an arrhythmogenic right ventricular dysplas
ia. An early diagnosis of myocarditis in athletes is useful to avoid t
he risk of fatal arrhythmias, also considering that rest still keeps o
n being one of the most effective strategies in myocarditis management
.