ANALYSIS OF POST-SYNTHETICALLY MODIFIED OLIGODEOXYNUCLEOTIDES BY ELECTROSPRAY-IONIZATION MASS-SPECTROMETRY

Authors
COLEMAN RS KESICKI EA ARTHUR JC COTHAM WE
Citation
Rs. Coleman et al., ANALYSIS OF POST-SYNTHETICALLY MODIFIED OLIGODEOXYNUCLEOTIDES BY ELECTROSPRAY-IONIZATION MASS-SPECTROMETRY, Bioorganic & medicinal chemistry letters, 4(15), 1994, pp. 1869-1872
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
4
Issue
15
Year of publication
1994
Pages
1869 - 1872
Database
ISI
SICI code
0960-894X(1994)4:15<1869:AOPMOB>2.0.ZU;2-D
Abstract
Electrospray-ionization mass spectrometry is used for the effective an alysis of post-synthetically modified oligodeoxynucleotides, wherein t hiol groups present on 4-thio-2'-deoxyuridine residues within the olig omers are used as site-specific points of attachment for functionalize d tethers.