G. Chaplain et al., CANCER OF CORPUS UTERI IN COTE-DOR 1982-1 990 - INCIDENCE, CLINICAL STAGE AND SURVIVAL, Bulletin du cancer, 81(8), 1994, pp. 691-697
In the French administrative ''departement'' of Cote-d'Or, between 198
2 and 1990, the crude incidence rate and the age-adjusted world standa
rdised incidence rate (ASR) for corpus uteri cancer were respectively
16.0 +/- 0.8 and 10.7 +/- 0.6 per 100000 women per year. The incidence
increased after 50 years of age, reaching a maximum of 66.7 per 10000
0 women per year at the age of 70-74 and thereafter declined. Ninety-s
ix percent of the patients were older than 50. The 5- and 10-year crud
e survival rates (all histologic types) were 66 +/- 3% and 61 +/- 4%.
The 5- and 10-year relative survival rates were 76%. Histologic types
were specified in 99.7% of cases, categorized as follows: 92.7% carcin
omas (333 cases), 6.7% sarcomas (24 cases) and 0.3% lymphoma (one case
). Carcinomas were clinically evaluated according to FIGO staging: sta
ge I: 61.4% (205 cases); stage II: 7.7% (59 cases); stage III: 7.8% (2
6 cases); stage IV: 6.6% (22 cases) and unspecified stage: 6,6% (22 ca
ses). The ASR by stage, were 6.4 +/- 0.5 (stage I); 0.8 +/- 0.2 (stage
II); 1.3 +/- 0.2 (stages III and IV); 0.6 +/- 0.2 (unspecified stage)
. The 5-year relative survival rates related to FIGO stage were 90% (s
tage I); 85% (stage II); 25% (stage III) and 0% (stage IV). Elderly pa
tients (> 75) had significantly lower survival rates. With respect to
localized disease (stages I and II) the relative risk of death associa
ted with age older than 75 was 4.9. The 5-year relative survival rate
of patients with sarcoma was 37%.